| Advanced Research | Biostation IM-Q Time Lapse Imaging System

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Product Summary

The Nikon BioStation IM-Q is a compact cell incubator and monitoring system that allows users with minimal microscopy experience to conduct live cell imaging without a steep learning curve. The BioStation IM-Q facilitates a broad array of short-term and long-term time-lapse experiments, including studies of cell growth, morphology, and protein expression, by providing consistent environmental control of temperature, humidity and gas concentration in combination with phase and fluorescence imaging of exceptional quality. Additionally, researchers can select from two types of microscope cameras. Perfusion capabilities further expand experimental possibilities.



Total System Integration

The BioStation IM-Q incorporates a motorized inverted microscope, an incubation chamber, and a high-sensitivity cooled CCD camera into a single package. Being an all-in-one, complete solution from one vendor, IM-Q overcomes stability and compatibility issues experienced in multi-vendor systems. Additionally, BioStation has a small footprint and is very easy to set up, requiring no alignment.

Environmental Control

Cells are easily maintained at the appropriate temperature, humidity and CO2 (or O2) levels with BioStation IM-Q. 5% CO2 (or O2), either from a premixed tank or the optional CO2 (or O2) mixer is humidified by bubbling through a bottle of water located at the front of the instrument. Sensors located throughout the instruments keep the temperature of the sample at 37° C.

*Optional Tri-gas mixers and CO2 mixers are available without sensors.

Phase and Fluorescence Imaging Capabilities

Phase contrast images of unsurpassed quality are obtained with BioStation IM-Q, which uses a red LED as the transmitted light source. BioStation's phase elements never need alignment, and the red transmitted light was proven to be cell friendly. With 2 channel fluorescence imaging, using standard Nikon filter cubes and Intensilight illumination system, BioStation IM is the solution for many researchers' advanced applications.

The BioStatiom IM-Q contains Nikon's ultra-high quality, high-sensitivity monochrome DS-Qi1 digital camera.

Thermal and Mechanical Stability

BioStation IM-Q features a no focus drift design and a vibration damping chassis. Combined with the thermal stability provided by the totally integrated incubation system, the mechanical stability offered by BioStation IM-Q allows researchers to image for hours or even days without focus drift. The fixed stage prevents even semi-adherent cells so multi-point time-lapse is optimized.

Powerful, Intuitive Software and Internal Motorized X, Y and Z for Multidimensional Imaging Experiments

Dedicated control software ensures easy operation, allowing the user to select between GUI's for live observation, time-lapse settings, and acquired image viewer. Multichannel, multipoint timelapse imaging can be set up easily by following the instructions on the GUI. The objective has 6mm of travel in X and Y, allowing large areas of the field to be sample. Additionally, moving the objective instead of the stage lends stability and repeatability to the system. Large composite movies from multiple fields of view is now possible.

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